Educational content only. Not medical advice. Consult a qualified physician.
Cathelicidin LL-37 peptide
ImmuneResearch-only. Not FDA-approved for therapeutic use. Active area of antimicrobial peptide research.

LL-37

Cathelicidin LL-37

LL-37 is the only human cathelicidin antimicrobial peptide, consisting of 37 amino acids. It is produced by immune cells, epithelial cells, and other tissues as part of the innate immune defense. Beyond direct antimicrobial activity, research suggests it plays roles in immune modulation, wound healing, and inflammation regulation.
Reported Benefits

Potential Benefits

  • Broad-spectrum antimicrobial activity against bacteria, viruses, and fungi documented in research
  • May support innate immune defense mechanisms
  • Research suggests wound healing and tissue repair properties
  • Studies indicate immunomodulatory effects that may help balance inflammatory responses
  • Preclinical data suggests potential anti-biofilm properties
Research Dosing

Recommended Starting Dose

100 mcg subcutaneously (not well-established; protocols vary widely)

Based on published research protocols. Not a prescription.

Dosing Protocol

No established clinical dosing protocol for therapeutic peptide use. Research and anecdotal protocols vary considerably. Some practitioners use 100 mcg subcutaneously several times per week. This peptide is primarily used in research settings.

DOSING INFORMATION DISCLAIMER: Any dosing information, protocols, or ranges discussed on this site are drawn from published research studies and clinical literature. They are presented for educational reference only and must not be used as self-medication guidance.

Research Timeline

Expected Timeline

Phase 1

As an immune-modulating peptide, effects on immune biomarkers may be measurable within weeks. Clinical experience is very limited.

Regulatory

Research Status

Research-only. Not FDA-approved for therapeutic use. Active area of antimicrobial peptide research.

The regulatory status of peptides can change at any time. Verify current FDA classification and legal status in your jurisdiction before seeking medical consultation about this compound.

Safety Profile

Potential Side Effects

  • Very limited human clinical data for exogenous administration
  • Injection site reactions possible
  • Potential for pro-inflammatory effects at high concentrations
  • Elevated LL-37 levels have been associated with certain inflammatory conditions (e.g., psoriasis, rosacea)
  • Safety profile for therapeutic administration is not established
Related Research

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Medical Disclaimer

EDUCATIONAL CONTENT ONLY: The peptide information presented on this page is compiled from published scientific literature, peer-reviewed research, and publicly available clinical data. It is provided strictly for educational purposes and does not constitute medical advice, an endorsement of any specific peptide, or a recommendation for treatment. Many peptides discussed on this site have not received FDA approval for human therapeutic use. Some may be under active regulatory review or subject to restrictions on compounding under FDA Section 503A and 503B frameworks. The regulatory status of individual peptides can change at any time. Readers should verify the current legal status of any peptide in their jurisdiction before pursuing further information or consultation. If you are considering peptide therapy, seek guidance from a licensed physician or healthcare provider who specializes in peptide-based treatments and operates within applicable federal and state regulations.