Educational content only. Not medical advice. Consult a qualified physician.
Epithalon (Epitalon) peptide
Anti-AgingResearch-only. Not FDA-approved. Most published studies originate from Russian research institutions. Limited Western peer-reviewed data.

Epithalon

Epithalon (Epitalon)

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural peptide Epithalamin, which is produced by the pineal gland. It was developed by Russian scientist Vladimir Khavinson. Research has focused on its potential to activate telomerase, the enzyme responsible for maintaining telomere length, which is associated with cellular aging.
Reported Benefits

Potential Benefits

  • Preclinical research suggests activation of telomerase in human somatic cells
  • Animal studies indicate potential for extending lifespan in certain models
  • May support regulation of the neuroendocrine system
  • Research suggests possible normalization of melatonin production in aging individuals
  • Animal data indicates potential antioxidant effects
Research Dosing

Recommended Starting Dose

5-10 mg subcutaneously or intravenously per day during active cycles

Based on published research protocols. Not a prescription.

Dosing Protocol

A common protocol involves 5-10 mg injected once daily for 10-20 consecutive days, repeated every 4-6 months. Some protocols use 10 mg every other day for 20 days. Most data comes from Khavinson's research group in Russia.

DOSING INFORMATION DISCLAIMER: Any dosing information, protocols, or ranges discussed on this site are drawn from published research studies and clinical literature. They are presented for educational reference only and must not be used as self-medication guidance.

Research Timeline

Expected Timeline

Phase 1

Biomarker changes (if any) may take several months to measure. Subjective reports of improved sleep and energy vary widely. Anti-aging benefits, if they exist, would require long-term assessment.

Regulatory

Research Status

Research-only. Not FDA-approved. Most published studies originate from Russian research institutions. Limited Western peer-reviewed data.

The regulatory status of peptides can change at any time. Verify current FDA classification and legal status in your jurisdiction before seeking medical consultation about this compound.

Safety Profile

Potential Side Effects

  • Very limited human safety data
  • Injection site reactions possible
  • Theoretical concerns about telomerase activation in cancerous cells (not confirmed in studies)
  • Possible effects on sleep patterns due to melatonin modulation
  • Long-term safety profile is unknown
Related Research

More in Anti-Aging

Medical Disclaimer

EDUCATIONAL CONTENT ONLY: The peptide information presented on this page is compiled from published scientific literature, peer-reviewed research, and publicly available clinical data. It is provided strictly for educational purposes and does not constitute medical advice, an endorsement of any specific peptide, or a recommendation for treatment. Many peptides discussed on this site have not received FDA approval for human therapeutic use. Some may be under active regulatory review or subject to restrictions on compounding under FDA Section 503A and 503B frameworks. The regulatory status of individual peptides can change at any time. Readers should verify the current legal status of any peptide in their jurisdiction before pursuing further information or consultation. If you are considering peptide therapy, seek guidance from a licensed physician or healthcare provider who specializes in peptide-based treatments and operates within applicable federal and state regulations.